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U.S. death rate from prescription opioid overdose from 1999 to 2023, by gender (per 100,000 population)

Death rate due to prescription opioid overdose U.S. 1999-2023, by gender

Last update: Nov 18, 2025

Regions: North America, United States of America

Statista Research Department

Survey time period: 1999 to 2023

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