Largest protocols in terms of total value locked (TVL) across multiple blockchains as of August 12, 2025 (in billion U.S. dollars)

Biggest DeFi protocols across multiple blockchains as of August 12, 2025

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Last update: Aug 12, 2025

Region: Worldwide

Survey time period: May 19, 2025

The biggest Decentralized Finance protocols in terms of TVL - how much crypto is deposited in the system - were MakerDAO and Compound. Protocols are autonomous programs based on a set of rules and smart contracts that enable the exchange of financial services among users - including stablecoins. Dai (DAI), for example, is the stablecoin of the MakerDAO protocol. Protocols can also include financial applications: Curve (CVR), for example, is a decentralized protocol aimed at crypto borrowing. The overall DeFi market size reached billion U.S. dollars as of November 2021.

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